Research Grade Raxibacumab ( 雷昔库单抗 )
- 发布日期： 2020-10-28
- 更新日期： 2025-10-24
产品详请
| 产地 |
中国
|
| 品牌 |
Chemstan
|
| 货号 |
CSD00167
|
| 保存条件 |
store at -80℃
|
| 用途 |
仅用于科研用途
|
| 应用范围 |
|
| 抗原来源 |
CHO cells
|
| CAS编号 |
565451-13-0
|
| 保质期 |
一年
|
| 抗体名 |
Raxibacumab ( 雷昔库单抗 )
|
| 是否单克隆 |
|
| 克隆性 |
|
| 靶点 |
Anthrax protective antigen [Bacillus anthracis]
|
| 适应物种 |
|
| 形态 |
|
| 宿主 |
|
| 标记物 |
|
| 包装规格 |
1mg/ml
|
| 纯度 |
%
|
| 亚型 |
|
| 标识物 |
|
| 浓度 |
95%
|
| 免疫原 |
|
| 是否进口 |
否
|
Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons. Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012.
货号（Catalog No.）
CSD00167
通用名INN
Raxibacumab
纯度(Purity)
>95%
浓度( Concentration)
1mg/ml
Formulation
PBS buffer pH7.5
Source
CHO cells
内毒素(Endotoxin level)
Please contact with the lab for this information.
生物活性
产品描述(Description)
Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons. Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012.
靶点;物种(Specificity target name;species)
Anthrax protective antigen [Bacillus anthracis]
活性研究（体外/体内研究）(Activity in vitro)
In vitro, PA-824 exhibits the high activity against multidrug-resistant clinical isolates from Asia (India and South Korea) and from throughout the United States (MIC <1 μg/ml) and is equally active against the drug-sensitive and multidrug-resistant isolates of M. tuberculosis (MICs range, 0.039 to 0.531 μg/ml). A recent study shows that single-nucleotide polymorphisms of PA-824 resistance genes (fgd1 [Rv0407] and ddn [Rv3547]) don't significantly affect the PA-824 MICs (≤ 0.25 μg/ml).
种类(Species)
Homo sapiens
受体鉴定(Receptor identification)
IgG1-lambda
化学信息
分子量(MV)
142844.53 Da
CAS
565451-13-0
存储条件(Storage)
store at -80°C
Note
For research use only. Not suitable for clinical or therapeutic use.
