CSD00214

通用名INN

Enlimomab Pegol

纯度(Purity)

>95%

浓度( Concentration)

1mg/ml

Formulation

PBS buffer pH7.5

Source

CHO cells

内毒素(Endotoxin level)

Please contact with the lab for this information.

靶点;物种(Specificity target name;species)

ICAM1/CD54[Homo sapiens]

活性研究（体外/体内研究）(Activity in vitro)

ICAM-1-IN-1 shows significant efficacy in a rat rheumatoid arthritis model and in a mouse asthma model. ICAM-1-IN-1 reduces the width of inflamed ankles after the ninth day following treatment, but shows no efficacy in the acute phase. Treatment with ICAM-1-IN-1 (25 mg/kg) for 21 days significantly reduces the ankle inflammation of the arthritis rats. Significant reduction of eosinophils and serum-soluble ICAM-1 (sICAM-1) is observed.

种类(Species)

Mus musculus

受体鉴定(Receptor identification)

Fab'-G2a-nd