武汉科斯坦生物科技有限公司
服务热线:15926423062
产品展厅
Recombinant Human LRP6 protein
  • 品牌:chemstan
  • 产地:中国
  • 货号:CSP00130
  • 价格: ¥1280/支
  • 发布日期: 2020-11-03
  • 更新日期: 2025-09-19
产品详请
产地 中国
品牌 chemstan
货号 CSP00130
用途 科研实验
包装规格 50ug
纯度 >90%
CAS编号
是否进口
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation.
联系方式
手机:15926423062
手机访问官网