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Recombinant Human CTCF protein
  • 品牌:chemstan
  • 产地:中国
  • 货号:CSP00486
  • 价格: ¥1280/支
  • 发布日期: 2020-11-03
  • 更新日期: 2025-08-15
产品详请
产地 中国
品牌 chemstan
货号 CSP00486
用途 科研实验
包装规格 50ug
纯度 >90%
CAS编号
是否进口
Chromatin binding factor that binds to DNA sequence specific sites. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Acts as transcriptional repressor binding to promoters of vertebrate MYC gene and BAG1 gene. Also binds to the PLK and PIM1 promoters. Acts as a transcriptional activator of APP. Regulates APOA1/C3/A4/A5 gene cluster and controls MHC class II gene expression. Plays an essential role in oocyte and preimplantation embryo development by activating or repressing transcription. Seems to act as tumor suppressor. Plays a critical role in the epigenetic regulation. Participates in the allele-specific gene expression at the imprinted IGF2/H19 gene locus.
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