Recombinant Human RARB protein
- 价格: ¥1280/支
- 发布日期: 2020-11-03
- 更新日期: 2025-12-23
产品详请
| 产地 |
中国
|
| 品牌 |
chemstan
|
| 货号 |
CSP00914
|
| 用途 |
科研实验
|
| 包装规格 |
50ug
|
| 纯度 |
>90%
|
| CAS编号 |
|
| 是否进口 |
否
|
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. The RXRA/RARB heterodimer can act as a repressor on the DR1 element and as an activator on the DR5 element. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function .