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Recombinant Human CHI3L1 protein
  • 品牌:chemstan
  • 产地:中国
  • 货号:CSP01414
  • 价格: ¥1280/支
  • 发布日期: 2020-11-03
  • 更新日期: 2025-07-28
产品详请
产地 中国
品牌 chemstan
货号 CSP01414
用途 科研实验
包装规格 50ug
纯度 >90%
CAS编号
是否进口
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
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