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Recombinant Human CD79A protein
  • 品牌:chemstan
  • 产地:中国
  • 货号:CSP01652
  • 价格: ¥1280/支
  • 发布日期: 2020-11-03
  • 更新日期: 2025-09-29
产品详请
产地 中国
品牌 chemstan
货号 CSP01652
用途 科研实验
包装规格 50ug
纯度 >90%
CAS编号
是否进口
CD79A (also known as Mb-1, Ig alpha and B cell antigen receptor complex-associated protein alpha-chain) is a 30-40 kDa member of the Ig-Superfamily. Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
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