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Recombinant Human LEF1 protein
  • 品牌:chemstan
  • 产地:中国
  • 货号:CSP01707
  • 价格: ¥1280/支
  • 发布日期: 2020-11-03
  • 更新日期: 2025-07-25
产品详请
产地 中国
品牌 chemstan
货号 CSP01707
用途 科研实验
包装规格 50ug
纯度 >90%
CAS编号
是否进口
Transcription factor that binds DNA in a sequence-specific manner. Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Required for IL17A expressing gamma-delta T-cell maturation and development, via binding to regulator loci of BLK to modulate expression. May play a role in hair cell differentiation and follicle morphogenesis.
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