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Recombinant Human CD177 protein
  • 品牌:chemstan
  • 产地:中国
  • 货号:CSP01795
  • 价格: ¥1280/支
  • 发布日期: 2020-11-03
  • 更新日期: 2025-07-25
产品详请
产地 中国
品牌 chemstan
货号 CSP01795
用途 科研实验
包装规格 50ug
纯度 >90%
CAS编号
是否进口
In association with beta-2 integrin heterodimer ITGAM/CD11b and ITGB2/CD18, mediates activation of TNF-alpha primed neutrophils including degranulation and superoxide production . In addition, by preventing beta-2 integrin internalization and attenuating chemokine signaling favors adhesion over migration. Heterophilic interaction with PECAM1 on endothelial cells plays a role in neutrophil transendothelial migration in vitro . However, appears to be dispensable for neutrophil recruitment caused by bacterial infection in vivo . Acts as a receptor for the mature form of protease PRTN3 allowing its display at the cell surface of neutrophils . By displaying PRTN3 at the neutrophil cell surface, may play a role in enhancing endothelial cell junctional integrity and thus vascular integrity during neutrophil diapedesis .
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