Recombinant Human IL1R1 protein
- 价格: ¥1280/支
- 发布日期: 2020-11-03
- 更新日期: 2025-07-24
产品详请
产地 |
中国
|
品牌 |
chemstan
|
货号 |
CSP01887
|
用途 |
科研实验
|
包装规格 |
50ug
|
纯度 |
>90%
|
CAS编号 |
|
是否进口 |
否
|
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells .