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Recombinant Human IL1R1 protein
  • 品牌:chemstan
  • 产地:中国
  • 货号:CSP01887
  • 价格: ¥1280/支
  • 发布日期: 2020-11-03
  • 更新日期: 2025-07-24
产品详请
产地 中国
品牌 chemstan
货号 CSP01887
用途 科研实验
包装规格 50ug
纯度 >90%
CAS编号
是否进口
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells .
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