Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them . Key regulator of LPAR1 signaling . Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor . Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner . Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity . Inhibits relaxation of airway smooth muscle in response to blue light .