概述（Summary）icon

英文全称

Recombinant Human MUC1 protein

纯度（Purity）

>90% as determined by SDS-PAGE

内毒素（Endotoxin level）

Please contact with the lab for this information.

蛋白构建（Construction）

A DNA sequence encoding the human MUC1 (Ser24-Pro146) was fused with His tag

Accession #

P15941

表达宿主（Host）

E.coli

种属（Species）

Homo sapiens (Human)

预测分子量（Predicted Molecular Mass）

14.26 kDa

制剂（Formulation）

Supplied as solution form  in  PBS pH 7.5./ Lyophilized from PBS pH 7.5.

运输方式（Shipping）

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

稳定性&储存（Stability &Storage）

Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.

复溶（Reconstitution）

Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.

背景（Background）icon

背景介绍

The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack.
The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.

分子别名（Alternative Names）

ADMCKD Protein, Human; ADMCKD1 Protein, Human; CA15-3 Protein, Human; CD227 Protein, Human; EMA Protein, Human; H23AG Protein, Human; KL-6 Protein, Human; MAM6 Protein, Human; MCD Protein, Human; MCKD Protein, Human; MCKD1 Protein, Human; MUC-1 Protein, Human; MUC-1/SEC Protein, Human; MUC-1/X Protein, Human; MUC1/ZD Protein, Human; Mucin 1 Protein, Human; PEM Protein, Human; PEMT Protein, Human; PUM Protein, Human