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Cortisol sulfate
  • 英文名称:Cortisol sulfate
  • 品牌:Chemstan
  • 产地:中国
  • 货号:CS-N8460
  • cas:1253-43-6
  • 价格: ¥100/mg
  • 发布日期: 2021-03-08
  • 更新日期: 2025-09-19
产品详请
产地 中国
品牌 Chemstan
货号 CS-N8460
用途 科研
英文名称 Cortisol sulfate
包装规格 100 mg
纯度 98.00%%
CAS编号 1253-43-6
别名
分子式 C??H??O?S
是否进口
Description

Cortisol sulfate (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate is a specific ligand for intracellular transcortin[1] [2] [3] .

In Vivo

Cortisol sulfate (3 mg; i.m.; every other day; for 2-7 weeks) affects behavior through its direct action on the central nervous system[4] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Wistar-King rats[4]
Dosage: 3 mg
Administration: Intramuscular injection, every other day, for 2-7 weeks
Result: Had significant stimulatory effects on the animal's exploratory behaviors (ambulation and rearing), when the treatments were started soon after weaning (postnatal day 21-24).
Molecular Weight

442.52

Formula

C??H??O?S

CAS No.

1253-43-6

中文名称

皮质醇21-硫酸

SMILES

C[C@]([C@@]1(O)C(CO[S](=O)(O)=O)=O)(C2)[C@](CC1)([H])[C@@](CCC3=CC4=O)([H])[C@]([C@]3(CC4)C)([H])[C@H]2O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • [1]. C S Hall, et al. Simultaneous metabolism of cortisol sulfate and cortisol in normal human adults. J Clin Endocrinol Metab. 1970 Oct;31(4):439-44.

    [2]. S S Singer, et al. Enzymatic sulfation of steroids: I. The enzymatic basis for the sex difference in cortisol sulfation by rat liver preparations. Endocrinology. 1976 Apr;98(4):963-74.

    [3]. T Hayashi, et al. Cortisol-21-sulfate (FS) is a specific ligand for intracellular transcortin: demonstration of three types of high affinity corticosteroid binders in bovine aortic cytosol by a combined use of FS and RU 28362. Endocrinology. 1990 Jan;126(1):307-16.

    [4]. S Miyabo, et al. Behavioral and other systemic effects of cortisol-21 sulfate. Horm Behav. 1972 Sep;3(3):227-36.

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