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产地 | 中国 |
品牌 | Chemstan |
货号 | CS-17485 |
用途 | 科研 |
英文名称 | Alminoprofen |
包装规格 | 10 mg |
纯度 | 98.00%% |
CAS编号 | 39718-89-3 |
别名 | |
分子式 | |
是否进口 | 否 |
Description |
Alminoprofen (EB-382) is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylpropionic acid class. Alminoprofen possesses a dual anti-inflammatory action, by inhibiting both secretory phospholipase A2 (sPLA2) and COX-2[1] . |
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IC50 & Target[1] |
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In Vitro |
Alminoprofen possesses a dual anti-inflammatory action, by inhibiting both sPLA2 but also COX-2. Alminoprofen (from 0 to 50 μM) induces a dose-related inhibitory response on thelevels of PGE2 formed by the CRL-1517 cell line[1] . MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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In Vivo |
Alminoprofen (100-300 mg/kg; p.o.) exerts an anti-inflammatory activity[1] . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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Molecular Weight |
219.28 |
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Formula |
C??H??NO? |
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CAS No. |
39718-89-3 |
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SMILES |
O=C(O)C(C)C1=CC=C(NCC(C)=C)C=C1 |
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Shipping |
Room temperature in continental US; may vary elsewhere. |
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Storage |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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References |
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