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SKF 100398
  • 英文名称:SKF 100398
  • 品牌:Chemstan
  • 产地:中国
  • 货号:CS-P3066
  • cas:77453-01-1
  • 价格: ¥500/mg
  • 发布日期: 2021-03-10
  • 更新日期: 2025-09-19
产品详请
产地 中国
品牌 Chemstan
货号 CS-P3066
用途 科研
英文名称 SKF 100398
包装规格 100 mg
纯度 98.00%%
CAS编号 77453-01-1
别名
分子式
是否进口
Description

SKF 100398 (d(CH2)5Tyr(Et)VAVP) is an arginine vasopressin (AVP) analogue, and acts as a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP[1] .

In Vivo

SKF 100398 is a specific antagonist of the hydrosmotic effect of exogenous and endogenous AVP[1] .
SKF 100398 (8 μg/kg; i.v.) abolishes the antidiuretic effect of AVP[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats (250-300 g)[1]
Dosage: 8 μg/kg
Administration: Intravenous injection
Result: Completely blocked the antidiuretic effect of exogenous AVP (4 ng/kg body wt i.v.).
Molecular Weight

1136.39

Formula

C??H??N??O??S?

CAS No.

77453-01-1

Sequence

{(1-Mercaptocyclohexyl)acetyl}-{Tyr(O-Ethyl)}-Phe-Val-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: 1-Cys6)

Sequence Shortening

{(1-Mercaptocyclohexyl)acetyl}-{Tyr(O-Ethyl)}-YFVNCPRG-NH2 (Disulfide bridge: 1-Cys6)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -80°C 2 years
-20°C 1 year
In solvent -80°C 6 months
-20°C 1 month
References
  • [1]. S Ishikawa, et al. Further in vivo evidence for antagonist-to-antidiuretic action of arginine vasopressin. Am J Physiol. 1983 Nov;245(5 Pt 1):R713-9.

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