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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | CS-137537 |
| 用途 | 科研 |
| 英文名称 | Pomalidomide-PEG2-azide |
| 包装规格 | 50 mg |
| 纯度 | 98.00%% |
| CAS编号 | 2267306-14-7 |
| 别名 | |
| 分子式 | |
| 是否进口 | 否 |
| Description |
Pomalidomide-PEG2-azide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1] . |
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| IC50 & Target[1] |
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| In Vitro |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1] . MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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| Molecular Weight |
444.40 |
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| Formula |
C??H??N?O? |
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| CAS No. |
2267306-14-7 |
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| SMILES |
O=C(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)COCCOCCN=[N+]=[N-] |
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| Shipping |
Room temperature in continental US; may vary elsewhere. |
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| Storage |
-20°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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| Solvent & Solubility |
In Vitro:
DMSO : 90 mg/mL (202.52 mM; Need ultrasonic)
Preparing
Stock Solutions
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
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| References |
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