NVS-CECR2-1, a non-BET family燘romodomain (BRD)爄nhibitor, is a potent and selective cat eye syndrome chromosome region, candidate 2 (CECR2) inhibitor. NVS-CECR2-1 binds to CECR2 BRD with high affinity (IC50=47 nM;燢D=80 nM). NVS-CECR2-1 exhibits cytotoxic activity and induces燼poptosis燼gainst various cancer cells by targeting CECR2 as well as via CECR2-independent mechanism