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653-47
  • 英文名称:653-47
  • 品牌:Chemstan
  • 产地:中国
  • 货号:CS-134598
  • cas:1224678-75-4
  • 价格: ¥2500/mg
  • 发布日期: 2021-03-10
  • 更新日期: 2025-09-19
产品详请
产地 中国
品牌 Chemstan
货号 CS-134598
用途 科研
英文名称 653-47
包装规格 5 mg
纯度 98.00%%
CAS编号 1224678-75-4
别名
分子式
是否进口
Description

653-47, a potentiator, significantly potentiates the cAMP-response element binding protein (CREB) inhibitory activity of 666-15. 653-47 is also a very weak CREB inhibitor with IC50 of 26.3 μM[1] .

In Vitro

653-47 (5-10 μM) synergistically inhibits CREB-mediated gene transcription with 666-15[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

370.83

Formula

C??H??ClN?O?

CAS No.

1224678-75-4

SMILES

O=C(C1=C(OCCCN)C=C2C=CC=CC2=C1)NC3=CC=C(Cl)C=C3O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • [1]. Xie F, et al. Discovery of a Synergistic Inhibitor of cAMP-Response Element Binding Protein (CREB)-Mediated Gene Transcription with 666-15. J Med Chem. 2019;62(24):11423-11429.

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