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(R)-3-Hydroxybutanoic acid sodium
  • 英文名称:(R)-3-Hydroxybutanoic acid sodium
  • 品牌:Chemstan
  • 产地:中国
  • 货号:CS-W015851
  • cas:13613-65-5
  • 价格: ¥500/mg
  • 发布日期: 2021-03-08
  • 更新日期: 2025-09-19
产品详请
产地 中国
品牌 Chemstan
货号 CS-W015851
用途 科研
英文名称 (R)-3-Hydroxybutanoic acid sodium
包装规格 500 mg
纯度 98.00%%
CAS编号 13613-65-5
别名
分子式
是否进口
Description

(R)-3-Hydroxybutanoic acid sodium ((R)-3-Hydroxybutyric acid) is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium has applications as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones[1] [2] .

In Vitro

(R)-3-Hydroxybutanoic acid sodium is a metabolite converted from acetoacetic acid. Enhanced hepatic fatty acid oxidation results in the increased production of acetoacetic acid which is in turn converted to (R)-3-Hydroxybutanoic acid sodium by a reaction catalyzed by 3-hydroxybutyrate dehydrogenase[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

126.09

Formula

C?H?NaO?

CAS No.

13613-65-5

中文名称

(R)-(-)-3-羟基丁酸钠盐

SMILES

C[C@H](CC(O[Na])=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (793.08 mM; Need ultrasonic)

H2O : 100 mg/mL (793.08 mM; Need ultrasonic)

Preparing 
Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 7.9308 mL 39.6542 mL 79.3084 mL
5 mM 1.5862 mL 7.9308 mL 15.8617 mL
10 mM 0.7931 mL 3.9654 mL 7.9308 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式 选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂: 10% DMSO    40% PEG300     5% Tween-80     45% saline

    Solubility: ≥ 2.5 mg/mL (19.83 mM); Clear solution

  • 2.

    请依序添加每种溶剂: 10% DMSO    90% (20% SBE-β-CD  in saline)

    Solubility: ≥ 2.5 mg/mL (19.83 mM); Clear solution

  • 3.

    请依序添加每种溶剂: 10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (19.83 mM); Clear solution

*以上所有助溶剂都可在 MCE 网站选购。
References
  • [1]. Ide T. Enzymatic-HPLC method to analyze D-3-hydroxybutyric acid in rat serum. Biosci Biotechnol Biochem. 2010;74(8):1578-82.

    [2]. Mateusz Biernacki, et al. Production of (R)-3-hydroxybutyric acid by Arxula adeninivorans. AMB Express. 2017 Dec;7(1):4.

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