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Thalidomide-NH-PEG4-COOH
  • 英文名称:Thalidomide-NH-PEG4-COOH
  • 品牌:Chemstan
  • 产地:中国
  • 货号:CS-134591
  • cas:2412056-48-3
  • 价格: ¥1000/mg
  • 发布日期: 2021-03-10
  • 更新日期: 2025-09-19
产品详请
产地 中国
品牌 Chemstan
货号 CS-134591
用途 科研
英文名称 Thalidomide-NH-PEG4-COOH
包装规格 100 mg
纯度 98.00%%
CAS编号 2412056-48-3
别名
分子式
是否进口
Description

Thalidomide-NH-PEG4-COOH is an E3 ligase ligand-linker conjugate which can be used for synthesizing dCBP-1 (HY-134582). dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1] .

IC50 & Target[1]

Cereblon

In Vitro

Thalidomide-NH-PEG4-COOH (S13) is the E3 ligase ligand-linker conjugate of dCBP-1 (HY-134582)[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

521.52

Formula

C??H??N?O??

CAS No.

2412056-48-3

SMILES

O=C(C1=CC(NCCOCCOCCOCCOCCC(O)=O)=CC=C12)N(C3CCC(NC3=O)=O)C2=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • [1]. Raghu Vannam, et al. Targeted degradation of the enhancer lysine acetyltransferases CBP and p300. Cell Chem Biol. 2020 Dec 31;S2451-9456(20)30513-4.

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