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Triclopyr
  • 英文名称:Triclopyr
  • 品牌:Chemstan
  • 货号:CS-B2051
  • cas:55335-06-3
  • 价格: ¥1000/mg
  • 发布日期: 2021-03-10
  • 更新日期: 2025-09-19
产品详请
产地
品牌 Chemstan
货号 CS-B2051
用途 科研
英文名称 Triclopyr
包装规格 100 mg
纯度 98%%
CAS编号 55335-06-3
别名
分子式
是否进口
Description

Triclopyr, a foliar systemic herbicide and fungicide, is widely used for broadleaf and woody plant control. Triclopyr has severe toxicity[1] .

In Vitro

Triclopyr (3 mM; 48 hours) treatment exhibits cytotoxicity against N2a cells[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: Mouse neuroblastoma (N2a) cells
Concentration: 3 mM
Incubation Time: 48 hours
Result: Decreased significantly for cell viability (P < 0.0001) compared to the untreated N2a cells.
In Vivo

Pharmacokinetic Analysis
Triclopyr exhibits moderate half-lives (dog 25 h and monkey 6.3 h) due to plasma clearance (18 mL/h/kg, 26 mL/h/kg respectively) following oral gavage (3 male beagle dogs ;0.5 mg/kg, 5 mg/kg and 20 mg/kg) and intravenous administration (1 male rhesus monkey; 30 mg/kg) [2] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 3 male beagle dogs(7.2 - 7.9 kg), 1 male rhesus monkey [2]
Dosage: 0.5 mg/kg, 5 mg/kg, 20 mg/kg (beagle dog); 30 mg/kg (rhesus monkey)
Administration: Oral gavage (beagle dog); intravenous (rhesus monkey)
Result: T1/2s of 25 and 6.3 h for dogs and a monkey, respectively.
Molecular Weight

256.47

Formula

C?H?Cl?NO?

CAS No.

55335-06-3

中文名称

绿草定

SMILES

OC(COC1=NC(Cl)=C(Cl)C=C1Cl)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • [1]. Tejaswini P Reddy, et al. Toxicity of neurons treated with herbicides and neuroprotection by mitochondria-targeted antioxidant SS31. Int J Environ Res Public Health. 2011 Jan;8(1):203-21.

    [2]. C Timchalk, et al. Pharmacokinetics of triclopyr (3,5,6-trichloro-2-pyridinyloxyacetic acid) in the beagle dog and rhesus monkey: perspective on the reduced capacity of dogs to excrete this organic acid relative to the rat, monkey, and human. Toxicol Appl Pharmacol. 1997 Jun;144(2):268-78.

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