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| 产地 | |
| 品牌 | Chemstan |
| 货号 | CS-131998 |
| 用途 | 科研 |
| 英文名称 | Thalidomide-NH-PEG4-Ms |
| 包装规格 | 100 mg |
| 纯度 | 98%% |
| CAS编号 | 2140807-24-3 |
| 别名 | |
| 分子式 | |
| 是否进口 | 否 |
| Description |
Thalidomide-NH-PEG4-Ms is an E3 ligase ligand-linker conjugate that incorporates Thalidomide based cereblon ligand and a linker used for PROTAC BCL-XL degrader XZ739[1] . |
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|---|---|---|
| IC50 & Target |
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| In Vitro |
XZ739, a CRBN-dependent PROTAC BCL-XL degrader with a DC50 value of 2.5 nM in MOLT-4 cells after 16 h treatment. XZ739 also induces cell death through caspase-mediated apoptosis[1] . MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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| Molecular Weight |
527.54 |
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| Formula |
C??H??N?O??S |
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| CAS No. |
2140807-24-3 |
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| SMILES |
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCOS(C)(=O)=O)=O |
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| Shipping |
Room temperature in continental US; may vary elsewhere. |
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| Storage |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| References |
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