Ethyl 3,4-dihydroxybenzoate (Ethyl protocatechuate), an antioxidant, is a爌rolyl-hydroxylase爄nhibitor found in the testa of peanut seeds. Ethyl 3,4-dihydroxybenzoate protects myocardium by activating燦O synthase燼nd generating mitochondrial燫OS. Ethyl 3,4-dihydroxybenzoate induces cell燼utophagy燼nd燼poptosis爄n ESCC cells. Ethyl 3,4-dihydroxybenzoate is a collagen synthesis inhibitor and has a bone protecting-effect