Quinizarin (1,4-Dihydroxyanthraquinone), a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNAby intercalating mode (K_d=86.1 μM). Quinizarin is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth^{[1] [2]} .

1,4-Dihydroxyanthraquinone (1,4-DHAQ, a fluorophore) doped cellulose (CL) (denoted as 1,4-DHAQ@CL) microporous nanofiber film has been achieved via simple electrospinning and subsequent deacetylating, and used for highly sensitive and selective fluorescence detection of Cu(2+) in aqueous solution^[1] .

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

240.21

C??H?O?

81-64-1

1,4-二羟基蒽醌；醌茜

O=C1C2=C(C=CC=C2)C(C3=C(O)C=CC(O)=C13)=O

Room temperature in continental US; may vary elsewhere.

• [1]. Verebová V, et al. Anthraquinones quinizarin and danthron unwind negatively supercoiled DNA and lengthen linear DNA. Biochem Biophys Res Commun. 2014;444(1):50-55.

  [2]. Dominic Cheuk, et al. Investigation into solid and solution properties of quinizarin.

  [3]. Wang M, et al. Electrospun 1,4-DHAQ-doped cellulose nanofiber films for reusable fluorescence detection of trace Cu2+ and further for Cr3+. Environ Sci Technol. 2012;46(1):367-373.