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| 产地 | 中国 |
| 品牌 | Chemstan |
| 货号 | CS-124793A |
| 用途 | 科研 |
| 英文名称 | GAK inhibitor 49 hydrochloride |
| 包装规格 | 5 mg |
| 纯度 | 98%% |
| CAS编号 | |
| 别名 | |
| 分子式 | |
| 是否进口 | 否 |
| Description |
GAK inhibitor 49 hydrochloride is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a Ki of 0.54 nM and a cell IC50 of 56 nM. GAK inhibitor 49 hydrochloride also shows binding to RIPK2[1] . |
|---|---|
| In Vitro |
GAK inhibitor 49 (compound 49) hydrochloride shows a weak inhibitory effect on AAK1, BMP2K and STK16, with IC50s of 28, 63 and >100μM, respectively[1] . MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Molecular Weight |
406.86 |
| Formula |
C??H??ClN?O? |
| SMILES |
COC1=C(OC)C(OC)=CC(NC2=CC=NC3=CC(OC)=C(OC)C=C23)=C1.[H]Cl |
| Shipping |
Room temperature in continental US; may vary elsewhere. |
| Storage |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| References |
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