Silybin-武汉科斯坦生物科技有限公司

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Silybin

英文名称：Silybin

产地：中国

cas：22888-70-6

价格： ￥950/块
发布日期： 2020-12-29
更新日期： 2025-09-29

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产地	中国
品牌
货号
用途	科研
英文名称	Silybin
包装规格
纯度	%
CAS编号	22888-70-6
别名
分子式
是否进口	否

中文名	水飞蓟宾
英文名	Silibinin
中文别名	水飞蓟宾(混有A和B) \| 2,3-二氢-3-(4-羟基-3-甲氧基苯基)-2-羟甲基-6-(3,5,7-三羟基-4-氧代苯并吡喃-2-基)苯并二氧六环 \| 水飞蓟素,西利马林.益肝灵 \| 水飞蓟素 \| 西利马林
英文别名	更多

描述	Silibinin为抗癌和化疗预防化合物，能抑制细胞增殖和迁移。
相关类别	信号通路 >> 自噬 >> 自噬研究领域 >> 癌症天然产物 >> 黄酮类化合物
参考文献	[1]. Woo SM, et al. Silibinin induces apoptosis of HT29 colon carcinoma cells through early growth response-1 (EGR-1)-mediated non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) up-regulation. Chem Biol Interact. 2014 Jan 16;211C:36-43. [2]. Kim TH, et al. Silibinin induces cell death through ROS-dependent down-regulation of Notch-1/ERK/Akt signaling in human breast cancer cells. J Pharmacol Exp Ther. 2014 Jan 28. [3]. Zhang S, et al. Silybin-mediated inhibition of Notch signaling exerts antitumor activity in human hepatocellular carcinoma cells. PLoS One. 2013 Dec 27;8(12):e83699. [4]. Khan AQ, et al. Silibinin Inhibits Tumor Promotional Triggers and Tumorigenesis Against Chemically Induced Two-Stage Skin Carcinogenesis in Swiss Albino Mice: Possible Role of Oxidative Stress and Inflammation. Nutr Cancer. 2013 Dec 23. [5]. Khazim K, et al. The antioxidant silybin prevents high glucose-induced oxidative stress and podocyte injury in vitro and in vivo. Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F691-700.

描述

Silibinin为抗癌和化疗预防化合物，能抑制细胞增殖和迁移。

相关类别

信号通路 >> 自噬 >> 自噬

研究领域 >> 癌症

天然产物 >> 黄酮类化合物

参考文献

[1]. Woo SM, et al. Silibinin induces apoptosis of HT29 colon carcinoma cells through early growth response-1 (EGR-1)-mediated non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) up-regulation. Chem Biol Interact. 2014 Jan 16;211C:36-43.

[2]. Kim TH, et al. Silibinin induces cell death through ROS-dependent down-regulation of Notch-1/ERK/Akt signaling in human breast cancer cells. J Pharmacol Exp Ther. 2014 Jan 28.

[3]. Zhang S, et al. Silybin-mediated inhibition of Notch signaling exerts antitumor activity in human hepatocellular carcinoma cells. PLoS One. 2013 Dec 27;8(12):e83699.

[4]. Khan AQ, et al. Silibinin Inhibits Tumor Promotional Triggers and Tumorigenesis Against Chemically Induced Two-Stage Skin Carcinogenesis in Swiss Albino Mice: Possible Role of Oxidative Stress and Inflammation. Nutr Cancer. 2013 Dec 23.

[5]. Khazim K, et al. The antioxidant silybin prevents high glucose-induced oxidative stress and podocyte injury in vitro and in vivo. Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F691-700.