This peptide sequence comprises R9-Tat. R9-Tat is the arginine-substituted analog for the HIV Tat protein (48-60). Similar to Tat (48-60), R9-Tat is internalized by macrophages and translocated to the nucleus and cytoplasm. Additionally, R9-Tat is efficient in intracellular protein delivery, serving as a protein carrier for Carbonic anhydrase into the cell.