Gly-Arg-Gly-Asp-Asn-Pro
- 英文名称:Gly-Arg-Gly-Asp-Asn-Pro
- 价格: ¥1280/mg
- 发布日期: 2021-03-15
- 更新日期: 2025-09-29
产品详请
产地 |
中国
|
品牌 |
Chemstan
|
货号 |
CS10535
|
用途 |
科研
|
英文名称 |
Gly-Arg-Gly-Asp-Asn-Pro
|
包装规格 |
1mg
|
纯度 |
98%%
|
CAS编号 |
114681-65-1
|
别名 |
|
分子式 |
|
是否进口 |
否
|
G-R-G-D-N-P is a superior inhibitor of cell attachment to fibronectin and a weak inhibitor of cell attacment to vitronectin. It also inhibits binding of fibrinogen, fibronectin, vitronectin and von Willebrand factor to platelets and resists to carboxypeptidases. G-R-G-D-N-P induces apoptosis in various cell types and cell lines at 1mM by a mechanism involving cellular uptake and possible direct stimulation of procaspase-3 autoprocessing. It contains the motif RGD (Arg-Gly-Asp) which is found in many integrin ligands. G-R-G-D-N-P inhibits cell adhesion to fibronectin 80-90% at 1 mM.