产品名称：罗丹明110*荧光参照标准*

CAS：13558-31-1

规格：1g

储存条件：-15℃避光防潮

保质期：24个月

产品物理化学光谱特性

分子量：366.80

外观：红色固体

溶剂：DMSO

激发波长(nm)：498

发射波长(nm)：520

产品介绍

罗丹明110是美国AAT Bioquest生产的罗丹明类染料 ，该化合物是各种基于R110的酶底物的前体。 它还用作基于R110的酶底物的校准标准。与AMC和AFC酶底物相比，荧光R110底物通常更敏感，比AMC和AFC底物具有更长的吸收和荧光波长。

参考文献

N-DEVD-N'-morpholinecarbonyl-rhodamine 110: novel caspase-3 fluorogenic substrates for cell-based apoptosis assay
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Journal: Bioorg Med Chem Lett (2005): 2335

A transgenic mouse model with a luciferase reporter for studying in vivo transcriptional regulation of the human CYP3A4 gene
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Fluorogenic substrate [Ala-Pro]2-cresyl violet but not Ala-Pro-rhodamine 110 is cleaved specifically by DPPIV activity: a study in living Jurkat cells and CD26/DPPIV-transfected Jurkat cells
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Journal: J Histochem Cytochem (2003): 959

Design and synthesis of rhodamine 110 derivative and caspase-3 substrate for enzyme and cell-based fluorescent assay
Authors: Cai SX, Zhang HZ, Guastella J, Drewe J, Yang W, Weber E.
Journal: Bioorg Med Chem Lett (2001): 39

Rhodamine 110-linked amino acids and peptides as substrates to measure caspase activity upon apoptosis induction in intact cells
Authors: Hug H, Los M, Hirt W, Debatin KM.
Journal: Biochemistry (1999): 13906

Intracellular accumulation of rhodamine 110 in single living cells
Authors: Jeannot V, Salmon JM, Deumie M, Viallet P.
Journal: J Histochem Cytochem (1997): 403

Flow cytometric determination of aminopeptidase activities in viable cells using fluorogenic rhodamine 110 substrates
Authors: Ganesh S, Klingel S, Kahle H, Valet G.
Journal: Cytometry (1995): 334

Flow cytometric determination of cysteine and serine proteinase activities in living cells with rhodamine 110 substrates
Authors: Klingel S, Rothe G, Kellermann W, Valet G.
Journal: Methods Cell Biol (1994): 449