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荧光底物Leu-AMC [L-亮氨酸-7-酰胺基-4-甲基香豆素]
  • 品牌:AAT Bioquest
  • 产地:American
  • 货号:CS13445
  • cas:62480-44-8
  • 价格: ¥1944/支
  • 发布日期: 2022-03-01
  • 更新日期: 2025-09-19
产品详请
产地 American
品牌 AAT Bioquest
货号 CS13445
用途 Research Grade
包装规格 10 mg
纯度 98%%
CAS编号 62480-44-8
是否进口

产品名称:荧光底物Leu-AMC [L-亮氨酸-7-酰胺基-4-甲基香豆素]

CAS:62480-44-8

规格:10mg

储存条件:-15℃避光防潮

保质期:24个月

 

产品物理化学光谱特性

分子量:324.80

溶剂:DMSO

激发波长(nm):351

发射波长(nm):430

 

产品介绍

荧光底物Leu-AMC [L-亮氨酸-7-酰胺基-4-甲基香豆素]是美国AAT Bioquest生产的荧光染料 ,Leu-AMC是亮氨酸氨肽酶的荧光底物。 在蛋白酶水解后,Leu-AMC释放出强烈荧光的AMC荧光团,其可以用Ex / Em = 350 / 430nm容易地检测。

 

参考文献

Molecular and biochemical characterization of methionine aminopeptidase of Babesia bovis as a potent drug target
Authors: Munkhjargal T, Ishizaki T, Guswanto A, Takemae H, Yokoyama N, Igarashi I.
Journal: Vet Parasitol (2016): 14

Secretory Expression, Purification, Characterization, and Application of an Aspergillus oryzae Prolyl Aminopeptidase in Bacillus subtilis
Authors: Wang KD, Wang KH, Zhou ND, Tian YP.
Journal: Appl Biochem Biotechnol. (2016)

Essential Role for an M17 Leucine Aminopeptidase in Encystation of Acanthamoeba castellanii
Authors: Lee YR, Na BK, Moon EK, Song SM, Joo SY, Kong HH, Goo YK, Chung DI, Hong Y.
Journal: PLoS One (2015): e0129884

Inhibition of leucine aminopeptidase 3 suppresses invasion of ovarian cancer cells through down-regulation of fascin and MMP-2/9
Authors: Wang X, Shi L, Deng Y, Qu M, Mao S, Xu L, Xu W, Fang C.
Journal: Eur J Pharmacol (2015): 116

Molecular Characterization of Babesia bovis M17 Leucine Aminopeptidase and Inhibition of Babesia Growth by Bestatin
Authors: Aboge GO, Cao S, Terkawi MA, Masatani T, Goo Y, AbouLaila M, Nishikawa Y, Igarashi I, Suzuki H, Xuan X.
Journal: J Parasitol (2015): 536

Modelling of human leucyl aminopeptidases for in silico off target binding analysis of potential Plasmodium falciparum leucine aminopeptidase (PfA-M17) specific inhibitors
Authors: Sahi S, Raj U, Chaudhary M, Nain V.
Journal: Recent Pat Endocr Metab Immune Drug Discov (2014): 191

Design, synthesis and preliminary activity evaluation of novel 3-amino-2-hydroxyl-3-phenylpropanoic acid derivatives as aminopeptidase N/CD13 inhibitors
Authors: Zhang X, Zhang L, Zhang J, Feng J, Yuan Y, Fang H, Xu W.
Journal: J Enzyme Inhib Med Chem (2013): 545

Enzymatic and molecular characterisation of leucine aminopeptidase of Burkholderia pseudomallei
Authors: Liew SM, Tay ST, Puthucheary SD.
Journal: BMC Microbiol (2013): 110

Exploration of structural and physicochemical requirements and search of virtual hits for aminopeptidase N inhibitors
Authors: Halder AK, Saha A, Jha T.
Journal: Mol Divers (2013): 123

Novel leucine ureido derivatives as inhibitors of aminopeptidase N (APN)
Authors: Ma C, Jin K, Cao J, Zhang L, Li X, Xu W.
Journal: Bioorg Med Chem (2013): 1621

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