产品名称：FunXite -1双色荧光活性探针*FUN® 1代替品*

规格：100uL

储存条件：-15℃避光防潮

保质期：24个月

产品物理化学光谱特性

分子量：528.84

溶剂：DMSO

产品介绍

FunXite -1在化学结构上与FUN®1相同（FUN®1是ThermoFisher的商标）。它是用于酵母和真菌的独特的双色荧光活性探针。FunXite-1扩散到各种细胞中，并最初以分散的绿色荧光染色细胞质。在某些酵母和真菌中，染色剂与某些细胞物质（例如谷胱甘肽）反应，产生明显的液泡结构，伴随着绿色细胞质荧光的减少，呈现出明显的红色荧光。由于真空内结构的形成需要质膜完整性和代谢能力，所以死亡的酵母和真菌细胞发出明亮的黄绿色荧光，而没有可辨别的红色结构。

参考文献

Efficacy of propidium iodide and FUN-1 stains for assessing viability in basidiospores of Rhizopogon roseolus
Authors: Fern and ez-Mir and a, E., Majada, J., Casares, A.
Journal: Mycologia (2017): 350-358

Use of the vital stain FUN-1 indicates viability of Phytophthora capsici propagules and can be used to predict maximum zoospore production
Authors: Lewis Ivey, M. L., Miller, S. A.
Journal: Mycologia (2014): 362-7

Assessment of FUN-1 vital dye staining: Yeast with a block in the vacuolar sorting pathway have impaired ability to form CIVS when stained with FUN-1 fluorescent dye
Authors: Essary, B. D., Marshall, P. A.
Journal: J Microbiol Methods (2009): 208-12

Saccharomyces cerevisiae samples stained with FUN-1 dye can be stored at -20 degrees C for later observation
Authors: Eggleston, M. D., Marshall, P. A.
Journal: J Microsc (2007): 100-3

Potent synergic effect between ibuprofen and azoles on Candida resulting from blockade of efflux pumps as determined by FUN-1 staining and flow cytometry
Authors: Pina-Vaz, C., Rodrigues, A. G., Costa-de-Oliveira, S., Ricardo, E., Mardh, P. A.
Journal: J Antimicrob Chemother (2005): 678-85

Adaptation of FUN-1 and Calcofluor white stains to assess the ability of viable and nonviable yeast to adhere to and be internalized by cultured mammalian cells
Authors: Henry-Stanley, M. J., Garni, R. M., Wells, C. L.
Journal: J Microbiol Methods (2004): 289-92

Susceptibility to fluconazole of Candida clinical isolates determined by FUN-1 staining with flow cytometry and epifluorescence microscopy
Authors: Pina-Vaz, C., Sansonetty, F., Rodrigues, A. G., Costa-de-Oliveira, S., Martinez-de-Oliveira, J., Fonseca, A. F.
Journal: J Med Microbiol (2001): 375-82

Development of the FUN-1 family of fluorescent probes for vacuole labeling and viability testing of yeasts
Authors: Millard, P. J., Roth, B. L., Thi, H. P., Yue, S. T., Haugl and R. P.
Journal: Appl Environ Microbiol (1997): 2897-905

A novel monoclonal antibody (FUN-1) identifies an activation antigen in cells of the B-cell lineage and Reed-Sternberg cells
Authors: Nozawa, Y., Wachi, E., Tominaga, K., Abe, M., Wakasa, H.
Journal: J Pathol (1993): 309-15