产品名称：钙离子荧光探针Cal-520L 马来酰亚胺

规格：100 ug

储存条件：-15℃避光防潮

保质期：24个月

产品物理化学光谱特性

分子量：991.78

溶剂：DMSO

激发波长(nm)：493

发射波长(nm)：515

荧光量子产率：0.75

产品介绍

钙测量对于许多生物学研究至关重要，一般结合钙后光谱响应的荧光探针使研究人员能够通过使用荧光显微镜，流式细胞仪，荧光光谱和荧光酶标仪来研究细胞内游离钙浓度的变化。作为低亲和力钙指示剂，Cal-520L已被证明是最好的绿色荧光钙指示剂之一。该硫醇反应性的Cal-520L马来酰亚胺可与IgG或其他载体分子偶联，以制备钙敏感生物共轭物，以检测特定靶标的钙空间变化。

参考文献

Optogenetic stimulation of Gs-signaling in the heart with high spatio-temporal precision.
Authors: Makowka, Philipp and Bruegmann, Tobias and Dusend, Vanessa and Malan, Daniela and Beiert, Thomas and Hesse, Michael and Fleischmann, Bernd K and Sasse, Philipp
Journal: Nature communications (2019): 1281

Polymer microchamber arrays for geometry-controlled drug release: a functional study in human cells of neuronal phenotype.
Authors: Kopach, Olga and Zheng, Kayiu and Sindeeva, Olga A and Gai, Meiyu and Sukhorukov, Gleb B and Rusakov, Dmitri A
Journal: Biomaterials science (2019): 2358-2371

A Water Framework Directive-compatible metric for assessing acidification in UK and Irish rivers using diatoms.
Authors: Juggins, Steve and Kelly, Martyn and Allott, Tim and Kelly-Quinn, Mary and Monteith, Don
Journal: The Science of the total environment (2016): 671-678

Mapping Calcium-Sensitive Regions in the Neuronal Calcium Sensor GCAP2 by Site-Specific Fluorescence Labeling.
Authors: Sulmann, Stefan and Wallisch, Melanie and Scholten, Alexander and Christoffers, Jens and Koch, Karl-Wilhelm
Journal: Biochemistry (2016): 2567-77

Red-Shifted Aequorin Variants Incorporating Non-Canonical Amino Acids: Applications in In Vivo Imaging.
Authors: Grinstead, Kristen M and Rowe, Laura and Ensor, Charles M and Joel, Smita and Daftarian, Pirouz and Dikici, Emre and Zingg, Jean-Marc and Daunert, Sylvia
Journal: PloS one (2016): e0158579

Site-specific fluorescent labeling to visualize membrane translocation of a myristoyl switch protein.
Authors: Yang, Sung-Tae and Lim, Sung In and Kiessling, Volker and Kwon, Inchan and Tamm, Lukas K
Journal: Scientific reports (2016): 32866

Excited-state structural dynamics of a dual-emission calmodulin-green fluorescent protein sensor for calcium ion imaging.
Authors: Oscar, Breland G and Liu, Weimin and Zhao, Yongxin and Tang, Longteng and Wang, Yanli and Campbell, Robert E and Fang, Chong
Journal: Proceedings of the National Academy of Sciences of the United States of America (2014): 10191-6

Optogenetic control of ROS production.
Authors: Wojtovich, Andrew P and Foster, Thomas H
Journal: Redox biology (2014): 368-76

Copper-64 radiolabelling of the C2A domain of synaptotagmin I using a functionalised bis(thiosemicarbazone): A pre- and post-labelling comparison.
Authors: Hueting, Rebekka and Tavaré, Richard and Dilworth, Jonathan R and Mullen, Gregory E
Journal: Journal of inorganic biochemistry (2013): 108-11