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SMPEG2
物品单位 价格 品牌
1200 AAT Bioquest
  • 产地:American
  • 型号:25 mg
  • 货号:CS4510
  • 发布日期: 2022-03-01
  • 更新日期: 2022-03-28
产品详细说明
产地 American
品牌 AAT Bioquest
货号 CS4510
用途范围 Research Grade
纯度 98%%
CAS编号
规格 25 mg
是否进口

产品名称:SMPEG2

规格:1mg

储存条件:-15℃避光防潮

保质期:12个月

 

产品物理化学光谱特性

分子量:425.39

外观:固体

溶剂:DMSO

 

产品介绍

SM(PEG)2是具有17.6埃的胺-巯基交联剂。它具有可与氨基反应的NHS酯和可与巯基反应的马来酰亚胺。N-羟基琥珀酰亚胺酯(NHS)基团在pH 7-9时与赖氨酸和N端氨基发生特异而有效的反应,形成稳定的酰胺键。马来酰亚胺基团在pH 6.5-7.5下与还原的巯基反应形成稳定的硫醚键。SM(PEG)2用于通过柔性PEG间隔臂不可逆地交联蛋白质或肽。PEG臂有助于保持缀合物的溶解度,减少聚集和免疫原性的趋势。它是执行受控的两步蛋白偶联(如SMCC)的理想选择。

 

参考文献

Biocompatible Organic Coatings Based on Bisphosphonic Acid RGD-Derivatives for PEO-Modified Titanium Implants.
Authors: Parfenova, Lyudmila V and Lukina, Elena S and Galimshina, Zulfia R and Gil'fanova, Guzel U and Mukaeva, Veta R and Farrakhov, Ruzil G and Danilko, Ksenia V and Dyakonov, Grigory S and Parfenov, Evgeny V
Journal: Molecules (Basel, Switzerland) (2020)

Cross-linking of bovine rhodopsin with sulfosuccinimidyl 4-(N maleimidomethyl)cyclohexane-1-carboxylate affects its functionality.
Authors: Medina, Rafael and Perdomo, Deisy and M?ller, Carolina and Bubis, José
Journal: The Biochemical journal (2020)

Dietary Pattern Specific Protein Biomarkers for Cardiovascular Disease: A Cross-Sectional Study in 2 Independent Cohorts.
Authors: Warensj? Lemming, Eva and Byberg, Liisa and Stattin, Karl and Ahmad, Shafqat and Lind, Lars and Elmst?hl, S?lve and Larsson, Susanna C and Wolk, Alicja and Micha?lsson, Karl
Journal: Journal of the American Heart Association (2019): e011860

Evaluation of the bioactivity about anti-sca-1/basic fibroblast growth factor-urinary bladder matrix scaffold for pelvic reconstruction.
Authors: Li, Jiankui and Chen, Xi and Ling, Kaijian and Liang, Zhiqing and Xu, Huicheng
Journal: Journal of biomaterials applications (2019): 808-818

Physical activity is associated with a large number of cardiovascular-specific proteins: Cross-sectional analyses in two independent cohorts.
Authors: Stattin, Karl and Lind, Lars and Elmst?hl, S?lve and Wolk, Alicja and Lemming, Eva Warensj? and Melhus, H?kan and Micha?lsson, Karl and Byberg, Liisa
Journal: European journal of preventive cardiology (2019): 1865-1873

Antitumor activity and carrier properties of novel hemocyanins coupled to a mimotope of GD2 ganglioside.
Authors: Palacios, Miriam and Tampe, Ricardo and Del Campo, Miguel and Zhong, Ta-Ying and López, Mercedes N and Salazar-Onfray, Flavio and Becker, María Inés
Journal: European journal of medicinal chemistry (2018): 74-86

Type 2 Diabetes in Relation to Hip Bone Density, Area, and Bone Turnover in Swedish Men and Women: A Cross-Sectional Study.
Authors: Mitchell, Adam and Fall, Tove and Melhus, H?kan and Wolk, Alicja and Micha?lsson, Karl and Byberg, Liisa
Journal: Calcified tissue international (2018): 501-511

Impacts of Cross-Linkers on Biological Effects of Mesoporous Silica Nanoparticles.
Authors: Chen, Yi-Ping and Wu, Si-Han and Chen, I-Chih and Chen, Chien-Tsu
Journal: ACS applied materials & interfaces (2017): 10254-10265

Antibody-coupled siRNA as an efficient method for in vivo mRNA knockdown.
Authors: B?umer, Nicole and Appel, Neele and Terheyden, Lisa and Buchholz, Frank and Rossig, Claudia and Müller-Tidow, Carsten and Berdel, Wolfgang E and B?umer, Sebastian
Journal: Nature protocols (2016): 22-36

Enhanced tumor targeting of cRGD peptide-conjugated albumin nanoparticles in the BxPC-3 cell line.
Authors: Yu, Xinzhe and Song, Yunlong and Di, Yang and He, Hang and Fu, Deliang and Jin, Chen
Journal: Scientific reports (2016): 31539


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