15926423062  

产品展厅

Cytidine 胞苷
物品单位 品牌
Chemstan
  • 产地:China
  • 型号:
  • 货号:CS00129
  • cas:65-46-3
  • 发布日期: 2022-08-01
  • 更新日期: 2022-08-03
产品详细说明
产地 China
货号 CS00129
品牌 Chemstan
用途 Research Grade
型号
CAS编号 65-46-3
别名 胞苷 , Cytosine-1-β-D-ribofuranoside , Cytosine β-D-riboside
规格
级别 其他
外观性状
产品英文名称 Cytidine
重金属 ppm
纯度 95%
分子式 C9H13N3O5

产品描述

Cytidine is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precursor for uridine. Both cytidine and uridine are utilized in RNA synthesis.

靶点活性

Nucleoside Analogue

体内活性

D-cycloserine (DCS) facilitates extinction of conditioned freezing to the light CS when no drug pre-exposure has occurred, but pre-exposure to DCS just prior to conditioning disrupted the facilitation of extinction effect in mice. [1] D-cycloserine (DCS) which has a high affinity for the glycine modulatory site in the NMDA receptor complex modulated memory processing in a dose-dependent manner. DCS also facilitates retention in 'senescence-accelerated mice' in which impairment of learning andmemory increases with age. [2] D-cycloserine (DCS) exhibits facilitated extinction of fear but are able to reacquire fear of that conditioned stimulus (CS) in a similar manner as saline-treated control rats. DCS-treated rats exhibits generalized extinction (i.e., they are less fearful of a non-extinguished CS) in comparison to controls. [3] D-cycloserine (DCS), an antimycobacterial agent known to cross the blood-brain barrier, binds with high affinity to this glycine modulatory site, functions as a positive modulator, and facilitates performance of learningtasks in rats. DCS appears to be a potent cognitive enhancer at doses lower than those required for antibacterial activity. [4] D-cycloserine injections (3.25, 15, or 30 mg/kg) before 30 non-reinforced light exposures dose-dependently enhances extinction but does not influence fear-potentiated startle in rats that does not receive extinction training. [5]

别名

胞苷 , Cytosine-1-β-D-ribofuranoside , Cytosine β-D-riboside

纯度

98%

分子量

243.22

分子式

C9H13N3O5

CAS No.

65-46-3

存储

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

溶解度

DMSO: 46 mg/mL (189.1 mM)

Water: 45 mg/mL (185 mM)

Ethanol: <1 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )

参考文献

1. Jonas DA, et al. Ann Nutr Metab. 2001; 45(6):235-54.

Note

For research use only.

< 返回前一个页面 >





联系方式
手机:15926423062
电话:15926423062
手机访问官网

15926423062

武汉科斯坦生物科技有限公司 版权所有(C)2022  XML 技术支持: 食品商务网   盖德化工网  

武汉科斯坦生物科技有限公司