产品描述

2'-O-Methyladenosine, a methylated adenine residue is found in the urine of normals and adenosine deaminase deficient patients. It shows unique hypotensive activities.

靶点活性

Human Endogenous Metabolite

体内活性

2'-O-Methyladenosine (100, 200 mg/kg, i.p., single dose) exhibits unique hypotensive activities in rats [2].

动物实验

Animal Model: Male spontaneously hypertensive rats (SHR; 16 weeks old). Dosage: 100, 200 mg/kg. Administration: I.P., single dose.[2]

别名

2'-O-甲基腺苷

纯度

98%

分子量

281.27

分子式

C11H15N5O4

CAS No.

2140-79-6

存储

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

溶解度

DMSO: 120 mg/mL (426.64 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

参考文献

1. Hirschhorn R, et al. Increased excretion of modified adenine nucleosides by children with adenosine deaminase deficiency. Pediatr Res. 1982 May;16(5):362-9.

2. Yamada T, et al. Naturally occurring 2'-O-methylpurine nucleosides with hypotensive properties. Cell Mol Life Sci. 1998 Feb;54(2):125-8.

Note

For research use only.