产品描述

2'-Deoxyadenosine is the DNA nucleoside A. It pairs with deoxythymidine (T) in double-stranded DNA.

别名

NSC-141848 , NSC141848 , NSC 141848 , 2'-脱氧腺苷

纯度

98%

分子量

251.24

分子式

C10H13N5O3

CAS No.

958-09-8

存储

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

溶解度

DMSO: Soluble

DMSO: 100 mg/mL (398.03 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

参考文献

1. Murakami H, Aoyanagi T, Miki Y, Tomita H, Esaka Y, Inoue Y, Teshima N. Effects of hydrophilic monomers on sorptive properties of divinylbenzene-based reversed phase sorbents. Talanta. 2018 Aug 1;185:427-432. doi: 10.1016/j.talanta.2018.03.093. Epub 2018 Mar 30. PubMed PMID: 29759223.

2. Markowitz M, Sarafianos SG. 4'-Ethynyl-2-fluoro-2'-deoxyadenosine, MK-8591: a novel HIV-1 reverse transcriptase translocation inhibitor. Curr Opin HIV AIDS. 2018 Apr 24. doi: 10.1097/COH.0000000000000467. [Epub ahead of print] PubMed PMID: 29697468.

3. Stegmüller S, Schrenk D, Cartus AT. Formation and fate of DNA adducts of alpha- and beta-asarone in rat hepatocytes. Food Chem Toxicol. 2018 Jun;116(Pt B):138-146. doi: 10.1016/j.fct.2018.04.025. Epub 2018 Apr 11. PubMed PMID: 29654846.

4. Carlson ES, Upadhyaya P, Villalta PW, Ma B, Hecht SS. Analysis and Identification of 2'-Deoxyadenosine-Derived Adducts in Lung and Liver DNA of F-344 Rats Treated with the Tobacco-Specific Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol. Chem Res Toxicol. 2018 Apr 19. doi: 10.1021/acs.chemrestox.8b00056. [Epub ahead of print] PubMed PMID: 29651838.

Note

For research use only.