产品描述

2′-Deoxy-2′-fluoroguanosine is a nucleoside analog that potently inhibits influenza virus A and B strains(EC90 <0.35 μM). 2'-Deoxy-2'-fluoroguanosine is an inhibitor of influenza virus replication in the upper respiratory tract, improving fever and nasal inflammation.

别名

2'-氟脱氧鸟苷 , 2'-脱氧-2'-氟鸟苷 ,

纯度

98%

分子量

285.23

分子式

C10H12FN5O4

CAS No.

78842-13-4

存储

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

溶解度

DMSO: 50 mg/mL (175.30 mM), Need ultrasonic

( < 1 mg/ml refers to the product slightly soluble or insoluble )

参考文献

1. Jakeman KJ, et, al. Efficacy of 2'-deoxy-2'-fluororibosides against influenza A and B viruses in ferrets. Antimicrob Agents Chemother. 1994 Aug;38(8):1864-7.

2. Tisdale M, et, al. Inhibition of influenza virus transcription by 2'-deoxy-2'-fluoroguanosine. Antimicrob Agents Chemother. 1995 Nov;39(11):2454-8.

Note

For research use only.