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产品展厅

3'-O-Methylguanosine 3'-甲氧基鸟苷
物品单位 品牌
Chemstan
  • 产地:China
  • 型号:
  • 货号:CS00036
  • cas:10300-27-3
  • 发布日期: 2022-08-01
  • 更新日期: 2022-08-04
产品详细说明
产地 China
货号 CS00036
品牌 Chemstan
用途 Research Grade
型号
CAS编号 10300-27-3
别名 3'-甲氧基鸟苷
规格
级别 其他
外观性状
产品英文名称 3
重金属 ppm
纯度 98%
分子式 C11H15N5O5

产品描述

Modified Nucleoside

生物活性

3'-O-Methylguanosine is an endogenous methylated nucleoside found in human fluids. Methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls. DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. 

别名

3'-甲氧基鸟苷

纯度

≥98%

分子量

297.27

分子式

C11H15N5O5

CAS No.

10300-27-3

存储

Store in a tight container at 2-8℃.

参考文献

[1] Morris GS, Simmonds HA, Davies PM: Use of biological fluids for the rapid diagnosis of potentially lethal inherited disorders of human purine and pyrimidine metabolism. Biomed Chromatogr. 1986 Jun;1(3):109-18.

[2] Yang TH, Hu ML: Intracellular levels of S-adenosylhomocysteine but not homocysteine are highly correlated to the expression of nm23-H1 and the level of 5-methyldeoxycytidine in human hepatoma cells with different invasion activities. Nutr Cancer. 2006;55(2):224-31.

[3] Liu Z, Liu S, Xie Z, Blum W, Perrotti D, Paschka P, Klisovic R, Byrd J, Chan KK, Marcucci G: Characterization of in vitro and in vivo hypomethylating effects of decitabine in acute myeloid leukemia by a rapid, specific and sensitive LC-MS/MS method. Nucleic Acids Res. 2007;35(5):e31. Epub 2007 Jan 30. 

Note

For research use only.

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