产品描述

Ascomycin(Immunomycin, FR-900520, FK520) is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties.

靶点活性

calcineurin phosphatase

别名

子囊霉素 , FK520 , FR-900520 , Immunomycin

纯度

98%

分子量

792.01

分子式

C43H69NO12

CAS No.

104987-12-4

存储

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

溶解度

DMSO: 39.6 mg/mL (50 mM)

Ethanol: 39.6 mg/mL (50 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

参考文献

1. Hatanaka H, et al. J Antibiot (Tokyo). 1988, 41(11), 1592-1601.

2. Revill WP, et al. J Pharmacol Exp Ther. 2002, 302(3), 1278-1285.

3. Monaghan P, et al. J Infect Dis. 2005, 191(8), 1342-1349.

4. Vázquez-López A, et al. Pharmacol Biochem Behav. 2006 Jul;84(3):511-6.

Note

For research use only.