产品描述

An antibacterial agent, a metabolite and a bacterial metabolite.

生物活性

Tyrocidine complex is a mixture of cyclic decapeptides originally isolated from B. brevis. It can be composed of 4 different amino acid sequences, giving tyrocidine A–D. Tyrocidine was the first commercially available antibiotic, but has been found to be toxic toward human blood and reproductive cells. The function of tyrocidine within its host B. brevis is thought to be regulation of sporulation.

别名

短杆菌酪肽

纯度

≥95%

分子量

1270.5

分子式

C66H87N13O13

CAS No.

8011-61-8

存储

Store in a tight container at -20℃.

参考文献

[1] Juhl DW, van Rensburg W, Bossis X, Vosloo JA, Rautenbach M, Bechinger B. Tyrocidine A interactions with saccharides investigated by CD and NMR spectroscopies. J Pept Sci. 2019 May;25(5):e3163.

[2] "Antibiotics". The Columbia Electronic Encyclopedia. 6th ed. Columbia University Press. 2007. pp. online.

[3] Roskoski R, Gevers W, Kleinkauf H, Lipmann F (December 1970). "Tyrocidine biosynthesis by three complementary fractions from Bacillus brevis (ATCC 8185)". Biochemistry. 9 (25): 4839–45. doi:10.1021/bi00827a002. PMID 4320358.

Note

For research use only.