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产品展厅

Telomestatin 替莫美他汀
物品单位 品牌
Chemstan
  • 产地:China
  • 型号:
  • 货号:CS01331
  • cas:265114-54-3
  • 发布日期: 2022-08-04
  • 更新日期: 2022-08-05
产品详细说明
产地 China
货号 CS01331
品牌 Chemstan
用途 Research Grade
型号
CAS编号 265114-54-3
别名 SOT 095 , GM95 , GM-95 , GM 95 , (R)-Telomestatin ,替莫美他汀
规格
级别 其他
外观性状
产品英文名称 Telomestatin
重金属 ppm
纯度 %
分子式 C26H14N8O7S

产品描述

Telomestatin is an inhibitor of the telomerase, it induces the formation of basket-type G-quadruplex (G4) structures from hybrid-type G-quadruplexes in the telomeric region.

别名

SOT 095 , GM95 , GM-95 , GM 95 , (R)-Telomestatin ,替莫美他汀

分子量

582.51

分子式

C26H14N8O7S

CAS No.

265114-54-3

存储

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

参考文献

1. Abraham Punnoose J, Ma Y, Li Y, Sakuma M, Mandal S, Nagasawa K, Mao H. Adaptive and Specific Recognition of Telomeric G-quadruplexes via Polyvalency Induced Unstacking of Binding Units. J Am Chem Soc. 2017 May 15. doi: 10.1021/jacs.7b00607. [Epub ahead of print] PubMed PMID: 28505453.

2. Maleki P, Ma Y, Iida K, Nagasawa K, Balci H. A single molecule study of a fluorescently labeled telomestatin derivative and G-quadruplex interactions. Nucleic Acids Res. 2017 Jan 9;45(1):288-295. doi: 10.1093/nar/gkw1090. Epub 2016 Nov 29. PubMed PMID: 27899628; PubMed Central PMCID: PMC5224478.

3. Mulholland K, Wu C. Binding of Telomestatin to a Telomeric G-Quadruplex DNA Probed by All-Atom Molecular Dynamics Simulations with Explicit Solvent. J Chem Inf Model. 2016 Oct 24;56(10):2093-2102. Epub 2016 Sep 27. PubMed PMID: 27632666.

4. Safa L, Gueddouda NM, Thiébaut F, Delagoutte E, Petruseva I, Lavrik O, Mendoza O, Bourdoncle A, Alberti P, Riou JF, Saintomé C. 5' to 3' Unfolding Directionality of DNA Secondary Structures by Replication Protein A: G-QUADRUPLEXES AND DUPLEXES. J Biol Chem. 2016 Sep 30;291(40):21246-21256. Epub 2016 Jul 19. PubMed PMID: 27440048; PubMed Central PMCID: PMC5076531.

Note

For research use only.

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