产品描述

Anthracycline antibiotic

生物活性

Dihydrocarminomycin is an anthracycline antibiotic that intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis.

别名

二氢洋红霉素

纯度

≥98%

分子量

515.52

分子式

C26H29NO10

CAS No.

62182-86-9

存储

Store in a tight container at -20°C.

参考文献

[1] Shepelevtseva N G, Belova I P, Vertogradova T P, et al. Comparative study of the cardiotoxicity of the anthracycline antibiotics, rubomycin, carminomycin and dihydrocarminomycin, in experiments on white mice. Antibiotiki. 1978 Jan;23(1):78-87.

[2] Povarov L S,Shorin V A,Bazhanov V S,Shepelevtseva N G.Preparation of dihydrocarminomycin and a comparison of its antitumor activity with the activity of carminomycin.[J]. Antibiotiki,1976,21(11):1008-11.

[3] Dudnik IuV, Ostanina LN. Interaction with DNA of semisynthetic carminomycin and rubomycin derivatives. Antibiotiki. 1983 Jan;28(1):31-6.

Note

For research use only.