产地 | China |
货号 | CS00023 |
品牌 | Chemstan |
用途 | Research Grade |
CAS编号 | 39389-47-4 |
别名 | 偏端霉素 A |
规格 | 支 |
级别 | 其他 |
重金属 | ppm |
英文名称 | Distamycin A |
纯度 | ≥90%% |
分子式 | C22H27N9O4 |
产品描述
Anticancer antibiotic,antiviral and antiprotozoal activity.
生物活性
Distamycin is an antibiotic that binds the minor groove of duplex DNA at AT‐rich regions and induces a specific activation of transcriptional initiation by binding to non-alternating AT sequences in the spacer DNA.
名称
偏端霉素 A
纯度
≥90%
分子量
481.51
分子式
C22H27N9O4
CAS No.
39389-47-4
存储
Store in a tight container at -20°C.
参考文献
[1] Cocco M J, Hanakahi L A, Huber M D, et al. Specific interactions of distamycin with G‐quadruplex DNA[J]. Nucleic acids research, 2003, 31(11): 2944-2951.
[2] Khalaf A I, Waigh R D, Drummond A J, et al. Distamycin analogues with enhanced lipophilicity: synthesis and antimicrobial activity[J]. Journal of medicinal chemistry, 2004, 47(8): 2133-2156.
[3] Dorn A, Affolter M, Müller M, et al. Distamycin‐induced inhibition of homeodomain‐DNA complexes[J]. The EMBO journal, 1992, 11(1): 279-286.
Note
For research use only.
15926423062
武汉科斯坦生物科技有限公司 版权所有(C)2024 XML 技术支持: 盖德化工网 食品商务网
武汉科斯坦生物科技有限公司