c-Myc tag Peptide
- 价格： ￥441/支
- 发布日期： 2022-10-10
- 更新日期： 2025-10-31
产品详请
| 产地 |
China
|
| 品牌 |
Chemstan
|
| 货号 |
CSGP10151
|
| 用途 |
Research Grade
|
| 包装规格 |
5mg
|
| 纯度 |
>98%%
|
| CAS编号 |
|
| 是否进口 |
否
|
产品描述
c-Myc Peptide is a useful displacement of c-Myc-tagged fusion proteins bound to anti-c-Myc antibodies in immunoassays. The successful inhibition of antibody binding by c-Myc peptide demonstrates binding is specific. c-Myc peptide participates in regulation of growth-related gene transcription.
The c-Myc Peptide is a synthetic peptide with an amino acid sequence that corresponds to the amino acids 410-419 of the C-terminal of human c-myc. Myc (c-Myc) is a regulator gene that codes for a transcription factor. c-Myc activation results in numerous biological effects. The first to be discovered was its capability to drive cell proliferation (upregulates cyclins, downregulates p21), but it also plays a very important role in regulating cell growth (upregulates ribosomal RNA and proteins), apoptosis (downregulates Bcl-2), differentiation and stem cell self-renewal. C-Myc is a very strong proto-oncogene and it is very often found to be upregulated in many types of cancers. c-Myc overexpression stimulates gene amplification, [1] presumably through DNA over-replication.
References:
1. Denis N, Kitzis A, Kruh J, Dautry F, Corcos D (August 1991). "Stimulation of methotrexate resistance and dihydrofolate reductase gene amplification by c-myc". Oncogene 6 (8): 1453–7.
Chemical Properties
Cas No.
N/A
SDF
别名
H-Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu-OH
化学名
c-Myc Peptide
Canonical SMILES
N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](C)CC)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
分子式
C51H86N12O21
分子量
1203.3
溶解度
≥ 60.165mg/mL in DMSO, ≥ 15.7 mg/mL in H2O with ultrasonic
储存条件
Desiccate at -20°C
General tips
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
Purity:
>98.00%
Note
For research use only .
