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c-Myc tag Peptide
  • 品牌:Chemstan
  • 产地:China
  • 型号:5mg
  • 货号:CSGP10151
  • 价格: ¥441/支
  • 发布日期: 2022-10-10
  • 更新日期: 2024-04-30
产品详请
产地 China
品牌 Chemstan
货号 CSGP10151
用途范围 Research Grade
纯度 >98%%
规格 5mg
是否进口
产品描述
c-Myc Peptide is a useful displacement of c-Myc-tagged fusion proteins bound to anti-c-Myc antibodies in immunoassays. The successful inhibition of antibody binding by c-Myc peptide demonstrates binding is specific. c-Myc peptide participates in regulation of growth-related gene transcription.
The c-Myc Peptide is a synthetic peptide with an amino acid sequence that corresponds to the amino acids 410-419 of the C-terminal of human c-myc. Myc (c-Myc) is a regulator gene that codes for a transcription factor. c-Myc activation results in numerous biological effects. The first to be discovered was its capability to drive cell proliferation (upregulates cyclins, downregulates p21), but it also plays a very important role in regulating cell growth (upregulates ribosomal RNA and proteins), apoptosis (downregulates Bcl-2), differentiation and stem cell self-renewal. C-Myc is a very strong proto-oncogene and it is very often found to be upregulated in many types of cancers. c-Myc overexpression stimulates gene amplification, [1] presumably through DNA over-replication.
References:
1. Denis N, Kitzis A, Kruh J, Dautry F, Corcos D (August 1991). "Stimulation of methotrexate resistance and dihydrofolate reductase gene amplification by c-myc". Oncogene 6 (8): 1453–7.
Chemical Properties

Cas No. 

N/A 

SDF  

别名 

H-Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu-OH 

化学名 

c-Myc Peptide 

Canonical SMILES 

N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](C)CC)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O 

分子式 

C51H86N12O21 

分子量 

1203.3 

溶解度 

≥ 60.165mg/mL in DMSO, ≥ 15.7 mg/mL in H2O with ultrasonic 

储存条件 

Desiccate at -20°C 

General tips 

For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. 

Shipping Condition 

Evaluation sample solution : ship with blue ice

All other available size: ship with RT , or blue ice upon request 

Purity: 

>98.00%

Note
For research use only .

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