Thalidomide-4-NH-PEG3-NH2 TFA
- 价格: ¥3200/支
- 发布日期: 2022-11-09
- 更新日期: 2025-05-09
产品详请
产地 |
China
|
品牌 |
Chemstan
|
货号 |
CSJY027
|
用途 |
Research Grade
|
包装规格 |
100mg
|
纯度 |
>95%%
|
CAS编号 |
2414913-97-4
|
是否进口 |
否
|
中文名称:沙利度胺-NH-PEG3-NH2 TFA
Pomalidomide-PEG3-C2-NH2 TFA 是一种合成的 E3 连接酶配体-linker 偶联物,包含基于 Pomalidomide 的 cereblon 配体和 3 个单元 PEG 的 linker。
生物活性:
Pomalidomide-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
IC50 & Target[1]:
Cereblon
分子量:
562.49
Formula:
C23H29F3N4O9
CAS 号:
2414913-97-4
运输条件:
Room temperature in continental US; may vary elsewhere.
储存方式:
4°C, stored under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
参考文献:
[1]. Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466. Content Brief
Note:
For research use only .