用途: VH-032（VHL配体1）是PROTAC的VHL配体和VHL/HIF-1α与185nM Kd相互作用的有效小分子抑制剂。

产品描述:
UCL-1972, a Histamine H3 Receptor Antagonist, used to treat cognitive disorders.

分子式:
C24H32N4O4S

分子量:
472.6

别名:
VH-032;VH 032

参考文献:
[1]Chan KH, Zengerle M, Testa A, Ciulli A. Impact of target warhead and linkage vector on inducing protein degradation: comparison of Bromodomain and Extra-Terminal (BET) degraders derived from triazolodiazepine (JQ1) and tetrahydroquinoline (I-BET726) BET inhibitor scaffolds. J Med Chem. 2017 Jun 8. doi: 10.1021/acs.jmedchem.6b01912. [Epub ahead of print] PubMed PMID: 28595007.

储存和溶解度:
( < 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years

Note：
For research use only .