SAR405-武汉科斯坦生物科技有限公司

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SAR405

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SAR405 is a Vps34 inhibitor (IC₅₀=1.2 nM),SAR405 inhibits autophagy caused by mTOR inhibition.

Cas No.	1523406-39-4	SDF
别名	N/A
化学名	(S)-1-((5-chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one
Canonical SMILES	C[C@H]1N(C(N=C2N3CC[C@@H](C(F)(F)F)N2CC4=CN=CC(Cl)=C4)=CC3=O)CCOC1
分子式	C₁₉H₂₁ClF₃N₅O₂	分子量	443.85
溶解度	≥ 22.2mg/mL in DMSO	储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

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