产品描述
Lisaftoclax is a dual Bcl-2 and Bcl-xl inhibitor (IC50: 2 nM and 5.9 nM) with antitumor activity.

体外活性
Lisaftoclax shows IC50s of 5.5 nM and 6.4 nM in Bcl-2 dependent RS4 11 cells and Bcl-xl dependent Molm 13 cells[1].

Cas No.
2180923-05-9

分子式
C45H48ClN7O8S

分子量
882.42

别名
APG-2575;Bcl-2/Bcl-xl inhibitor 1

参考文献
[1]WANG, Chia, et al. N-(PHENYLSULFONYL)BENZAMIDES AND RELATED COMPOUNDS AS BCL-2 INHIBITORS. Patent. WO2018027097A1.

储存和溶解度
DMSO:225mg/mL (255mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years

Note
For research use only .