武汉科斯坦生物科技有限公司
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产品展厅
MST-312
  • 品牌:TargetMol
  • 产地:China
  • 型号:2mg
  • 货号:T41290
  • cas:368449-04-1
  • 价格: ¥417/支
  • 发布日期: 2023-02-21
  • 更新日期: 2025-05-13
产品详请
产地 China
品牌 TargetMol
货号 T41290
用途 Research Grade
包装规格 2mg
纯度 >98%%
CAS编号 368449-04-1
是否进口
产品描述
MST-312 is an inhibitor of telomerase and can be used in studies about cancer, such as multiple myeloma.


体外活性
In U-266 cells, MST-312 (2 μM) upregulates the pro-apoptotic gene Bax and down-regulates the anti-apoptotic gene Bcl-2 and suppresses the expression of c-Myc and hTERT genes. MST-312 (2-8 μM) reduces cellular viability in a dose dependent and time-dependent manner. MST-312 (2-8 μM) induces cell apoptosis in a dose-dependent manner[1].


Cas No.
368449-04-1


分子式
C20H16N2O6


分子量
380.356


别名
Telomerase Inhibitor IX


参考文献
[1]Ameri Z, et al. Telomerase inhibitor MST-312 induces apoptosis of multiple myeloma cells and down-regulation of anti-apoptotic, proliferative and inflammatory genes. Life Sci. 2019;228:66-71.


储存和溶解度
DMSO:70 mg/mL (184.04 mM),ultrasonic and warming and heat to 60°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years


Note
For research use only .

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