MST-312
- 价格: ¥417/支
- 发布日期: 2023-02-21
- 更新日期: 2023-12-10
产品详请
产地 |
China
|
品牌 |
TargetMol
|
货号 |
T41290
|
用途范围 |
Research Grade
|
纯度 |
>98%%
|
CAS编号 |
368449-04-1
|
规格 |
2mg
|
是否进口 |
否
|
产品描述
MST-312 is an inhibitor of telomerase and can be used in studies about cancer, such as multiple myeloma.
体外活性
In U-266 cells, MST-312 (2 μM) upregulates the pro-apoptotic gene Bax and down-regulates the anti-apoptotic gene Bcl-2 and suppresses the expression of c-Myc and hTERT genes. MST-312 (2-8 μM) reduces cellular viability in a dose dependent and time-dependent manner. MST-312 (2-8 μM) induces cell apoptosis in a dose-dependent manner[1].
Cas No.
368449-04-1
分子式
C20H16N2O6
分子量
380.356
别名
Telomerase Inhibitor IX
参考文献
[1]Ameri Z, et al. Telomerase inhibitor MST-312 induces apoptosis of multiple myeloma cells and down-regulation of anti-apoptotic, proliferative and inflammatory genes. Life Sci. 2019;228:66-71.
储存和溶解度
DMSO:70 mg/mL (184.04 mM),ultrasonic and warming and heat to 60°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Note
For research use only .