LY402913
- 价格: ¥1298/支
- 发布日期: 2023-02-21
- 更新日期: 2023-12-01
产品详请
产地 |
China
|
品牌 |
TargetMol
|
货号 |
T9944
|
用途范围 |
Research Grade
|
纯度 |
>98%%
|
CAS编号 |
246238-55-1
|
规格 |
1mg
|
是否进口 |
否
|
产品描述
LY402913 is a selective modulators of the multidrug resistance protein (MRP1).
体外活性
LY402913 demonstrated reversal of MRP1-mediated drug resistance (in the presence of a sublethal dose of doxorubicin) in the MRP1-transfected cell line, HeLa-T5, EC50 = 0.90[1].
Cas No.
246238-55-1
分子式
C28H24ClN3O6
分子量
533.96
参考文献
[1]Norman BH, Lander PA, Gruber JM, Kroin JS, Cohen JD, Jungheim LN, Starling JJ, Law KL, Self TD, Tabas LB, Williams DC, Paul DC, Dantzig AH. Cyclohexyl-linked tricyclic isoxazoles are potent and selective modulators of the multidrug resistance protein (MRP1). Bioorg Med Chem Lett. 2005 Dec 15;15(24):5526-30. doi: 10.1016/j.bmcl.2005.08.075. Epub 2005 Oct 3. PMID: 16202586.
储存和溶解度
( < 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Note
For research use only .